How much is a flight from Chicago to Santa Cruz de la Sierra?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Chicago and Santa Cruz.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Chicago - Santa Cruz de la Sierra route.

Are there multiple airports in Chicago and Santa Cruz?

If your departure or arrival city has more than one airport, it's worth comparing all of them for timing and pricing.

• Airports in Chicago: 3 airports are active in Chicago - Midway, O'Hare, Rockford.
• Airports in Santa Cruz: Santa Cruz is a secondary airport to Santa Cruz - Viru Viru.

If you're traveling with a group or bulky luggage, look into parking or transport options. Alternative airports may offer faster transfers or better rates.

Plan your perfect flight from Chicago to Santa Cruz de la Sierra

Jetcost gives you full control over your flight search. Filter by date, time, duration, price, and airline. See round-trip and one-way options from low-cost and full-service carriers and more.

Other popular destinations

Planning a trip to Bolivia? Other frequent searches include: Cochabamba, La Paz, Santa Cruz, Sucre, Tarija.

Some airlines include baggage in the fare, others don’t — always check the details before booking. If you're looking for round-trip flights, you can easily see the most convenient combinations.