How much is a flight from Guatemala City to Santo Domingo La Isabela?

Prices vary based on date, airline, and availability. Compare several options if you're flying between Guatemala City and Santo Domingo.

Pick a travel date to see today’s available fares.

Fares change often — checking several times throughout the week can make a big difference. Booking in advance often means access to lower prices for the Guatemala City - Santo Domingo La Isabela route.

Flying from or to Guatemala City and Santo Domingo? Here are your airport options

Knowing your full list of nearby airports can make flight planning easier, especially when routes vary.

• Airports in Guatemala City: Only Guatemala City is available for departures.
• Airports in Santo Domingo: Santo Domingo - La Isabela is the only arrival option right now.

For families or those traveling with assistance, smaller airports can be easier to navigate. Cities served by multiple airports often allow for more flexible travel planning.

Adjust your flight filters for Guatemala City – Santo Domingo La Isabela

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Other popular destinations

Planning a trip to Dominican Republic? These cities are popular too: La Romana, Puerto Plata, Punta Cana, Santiago, Santo Domingo.

Sorting options let you see the most affordable flights first. Some results may include extra fees shown only at checkout — always read carefully to see what’s included.