Cheap flights from Santo Domingo La Isabela to Panama City

Flights tailored to your budget

Selected dates may not give results due to COVID-19. We suggest you change the dates.
Multi-city Round trip One way
Round trip
One way
Multi-city
From
No results match your search criteria
To
No results match your search criteria
{{ weekDay }}
Dates
{{ panel.label }}
Looking for a one-way flight?

Flexible dates can save you money

Explore nearby dates to find lower fares

{{ fromDate | dateToLongNamedDate }}
?
Flexible dates
Depart {{ flexibleFromDateLabel }}
{{ option.label }}
?
Return {{ flexibleToDateLabel }}
{{ option.label }}
Passengers / Class
Number of passengers
Adults
{{ adults }}
Children
{{ children }}
Infants
{{ infants }}
Class
Economy
Available for Economy only
New Multi-city experience

Discover a new Multi-city search experience from Jetcost, designed to handle more complex itineraries. By continuing, you’ll be taken to a dedicated page powered by Kiwi.com.
How do we get the info you see here? Please note that we offer an online comparison service and that all information and prices regarding services and/or products available on our website are provided by our third-party partners. We do our best to show you up-to-date information, but please note that we are not responsible for the completeness or accuracy of the information published, so please check all conditions carefully on the website of the partner before making a booking. Please check our Terms and Conditions for more details. Read more

How to get the best price from Santo Domingo La Isabela to Panama City?

Depending on when you travel and how far in advance you book, fares between Santo Domingo and Panama City can differ a lot.

Pick a travel date to see today’s available fares.

Search engines like Jetcost can highlight price changes in just seconds. For example, some users find better prices by flying on one day of the week over another — try several searches to spot the cheapest day.

Flying from or to Santo Domingo and Panama City? Here are your airport options

Knowing your full list of nearby airports can make flight planning easier, especially when routes vary.

  • Airports in Santo Domingo: Only Santo Domingo - La Isabela is available for departures.
  • Airports in Panama City: Arrivals into Panama City are possible from 2 airports - Pacífico International Airport, Paitilla.

For families or those traveling with assistance, smaller airports can be easier to navigate. Cities served by multiple airports often allow for more flexible travel planning.

Flights from Santo Domingo - La Isabela to Panama City - Tocumen

Customize your flight from Santo Domingo La Isabela to Panama City

Jetcost allows you to filter by travel dates, duration, layovers, carriers, and booking providers. You’ll find direct and connecting flights, one-way or round-trip, from the best airlines and travel agencies.

Other popular destinations

Thinking about Panama? You might also consider: Bocas Del Toro, Changuinola, Contadora, David, Panama City.

You can sort results by price, duration, or departure time to find the best option for you. When available, results always include both low-cost and traditional airlines.
Frequently Asked Questions

Frequently asked questions about flights from Santo Domingo La Isabela to Panama City.

How much does an airline ticket from Santo Domingo La Isabela to Panama City cost?

Flight prices can vary a lot depending on the period and destination. At the moment, this information is not available for flights from Santo Domingo La Isabela to Panama City.

How far is Santo Domingo from Panama City?

Santo Domingo is about 1463 km from Panama City.

What are the airports in Panama City?

Panama City has 2 airports: Pacífico International Airport, Paitilla.

What are the airports in Santo Domingo?

Santo Domingo has one airport: Santo Domingo - La Isabela.

What are the most popular cities in Panama?

The most popular cities in Panama according to our users' searches are: Bocas Del Toro, Changuinola, Contadora, David, Panama City.

When should I book a flight from Santo Domingo to Panama City?

This information is not available at the moment.

What is the cheapest month to fly from Santo Domingo to Panama City?

This information is not available at the moment.

What is the most expensive month to fly from Santo Domingo to Panama City?

This information is not available at the moment.

What is the best day of the week to fly from Santo Domingo to Panama City?

This information is not available at the moment.